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SULPHATYLOZIN

Description: a powder a pale yellow colour, hard dissolved in water.

Composition: the product contains active substance of sulfadimidine, trimethoprim, tylosin tatrtate, oxytetracycline hydrochloride.

Pharmacological properties: components which are a part of a preparation, cause its wide spectrum of antibacterial activity in relation to gram-positive (Stapfylococcus spp., Streptococcus spp., Clostridium spp., Campylobacter spp.) and gram-negative bacteria (E. coli, Bordetella spp., Salmonella spp., Klebsiella spp., Pasterella spp., Proteus spp., Campylobacter), and ray fungus, leptospirs, mycoplasms, rickettsia, spirochaetes and some viruses. The sulfadimidine blocks getting aminobenzoic acid by microorganisms and stops synthesis of folic acid. The trimetoprim inhibits dihydrofolatreductase of bacteria in 50000 times more effective, than corresponding enzyme of animals. This enzyme restores dihydrofolic acid in tetradihydrofolic acid which is the intermediate stage in synthesis of purines, and accordingly and DNA. The sulfadimidine and trimethoprim consistently block this process, considerably improving action each other (synergism). Antibiotics of oxitetracycline hydrochloride and tylosin tartrate has a high bacteriostatic activity. The complex product has a wide spectrum of bactericidal and bacteriostatic actions, including against microorganisms resistant to separate antibiotics and chemotherapeutic products. At introduction the product is quickly absorbed in blood and gets into all bodies and tissues of animals.

Application: prevention and treatment of cattle, horses, goats, sheep, pigs, dogs, cats, rabbits and chickens suffering from cystitis, mastitis, septicemia, colibacillosis, pasteurellosis, leptospirosis, mycoplasmosis, vibrioz, dysentery, swine erysipelas, edema disease, as well as postpartum complications are caused by pathogens susceptible to sulfadymedynu, trimethoprim, oxytetracycline and tylosin.

Administration route and dosage: the sulphatylozin is given to animals with a forage or  dissolved in water (milk) twice per day in a dose of 1,2-1,5 g on 10 kg of body mass with an interval of 12 hours. Treatments are carried out to disappearance of clinical symptoms of disease and throughout two next days.

Contraindication: do not apply for animals with hypersensitivity to the product, to hens-layers, and also animals at infringement of function of bodies of blood circulation, liver and kidneys.

Caution: the slaughter and consumption of milk for people permitted in 10 days and 5 days accordingly after the last application of product. Received meat and milk to the mentioned period utilize or fed to unproductive animals, according to the veterinary's conclusion.

Release form: packages of aluminium foil and polymeric container on 10-500; paper bags with a aluminum insert on 8-20 kg.

Storage: in a dry, dark place at a temperature from 10 ° C to 25 ° C.

Shelf life: 2 years.

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